https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation. https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53962 Tue 23 Jan 2024 12:39:27 AEDT ]]> The trans-ancestral genomic architecture of glycemic traits https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46927 Thu 08 Dec 2022 12:22:07 AEDT ]]> New genetic loci link adipose and insulin biology to body fat distribution https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:28089 Sat 24 Mar 2018 07:39:47 AEDT ]]> Genetic studies of body mass index yield new insights for obesity biology https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27460 −8), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ~2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.]]> Sat 24 Mar 2018 07:32:44 AEDT ]]> Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51706 Fri 15 Sep 2023 14:02:18 AEST ]]>